SECTION EDITOR: HASSAN M. FATHALLAH-SHAYKH, MD Brain Development in Healthy, Hyperactive, and Psychotic Children
نویسنده
چکیده
S erious and chronic childhood psychiatric disorders have long been assumed to reflect relatively subtle abnormalities of brain development. Although diagnostic brain imaging is well established in pediatric neurology, it has not yet permitted quantitative assessment of brain abnormalities in children with psychiatric illnesses. Recent advances in brain magnetic resonance imaging (MRI) allow reliable, automated, quantitative measurement of multiple brain regions. The noninvasive nature of MRI also allows periodic rescanning for research purposes, making prospective longitudinal study of brain development feasible in large numbers of healthy children and those with psychiatric illness. Longitudinal MRI of the brain also makes possible the mapping of region-specific changes in brain volume over time.
منابع مشابه
SECTION EDITOR: HASSAN M. FATHALLAH-SHAYKH, MD Functional Genomics, Fragile X Syndrome, and RNA Interference
A remarkable revolution is occurring in biomedical science that is likely to have profound implications for the way we treat human diseases in the future. In the past 2 years, we have learned that introduction of short double-stranded RNA (dsRNA) molecules into vertebrate cells can silence any gene homologous to the dsRNA. This process is called RNA interference (RNAi) and is based on the abili...
متن کاملProper orthogonal decomposition for parameter estimation in oscillating biological networks
متن کامل
JAMA Neurology.
Editorial Processing Manuscript Editing Manager Tracy Frey Senior Manuscript Editors Miriam Y. Cintron, Shannon L. Sparenga Manuscript Editors Kevin Brown, Paul Ruich, Suzanne Walker Freelance Manuscript Editing Manager Diane L. Cannon Freelance Manuscript Editing Coordinators Connie L. Manno, Fred Marshall Freelance Copy Editors and Copyreaders Catherine A. Alden, Stephanie Lang Beckmeyer, Jan...
متن کاملApplications and Pitfalls
M icroarrays are simple assays that measure the relative expression levels of tens of thousands of genes. Excitement about their importance and potential contributions to biology and medicine has been intense. Nonetheless, recent insights into the limitations and pitfalls of microarrays have led to caution about data interpretation. Microarrays are very useful but they are also very misleading;...
متن کامل